Medline, 2007
(Online Peer-Reviewed Biomedical Journal)
A SUCCINATE-BASED COMPOSITION "REJUVENATES" AGING MICE AND ALLEVIATES MENOPAUSAL SYMPTOMS IN WOMEN WITHOUT SEX HORMONE REPLACEMENT THERAPY
VOL. 8, ART. 46 (pp. 497-517) // september 2007 y.

In the randomized, placebo-controlled clinical study in menopausal women, Amberen significantly lowered most neurovegetative, psycho-emotional, and biochemical symptoms of menopause. Succinate-based therapy appeared to be free of adverse side effects.

This approach, which focuses on correcting metabolism and neuro-endocrine control by using a signal energy intermediate, Amberen, instead of exogenous hormones, is the first of its kind and represents a step forward in metabolic mitochondrial medicine. It offers hope in the development of safer treatments for a wide range of diseases, particularly those associated with aging.